Long-term Reproducibility of Allergen-specific IgE Measurements by ImmunoCAP
نویسندگان
چکیده
منابع مشابه
Increased allergen-specific IgG4 levels are linked to suppressed IgE titers when analysed by ISAC but not by immunocap
Allergen specific immunotherapy (ASIT) is the only disease modifying treatment of allergic diseases. A key element in the protective effect is thought to be induction of a specific IgG4 response leading to a decrease in the IgE-mediated allergic symptoms. The effect of ASIT can be ascertained by provocation or skin prick testing. IgE measurement by ImmunoCAP is a sensitive standard procedure fo...
متن کاملFood allergy and anaphylaxis – 2043. Poor dilutional linearity of food allergen specific IgE measurement by immunocap in samples with high total IgE
Methods 31 deidentified subjects with tIgE 1000-5000 kU/L (Group A) and 10 subjects with tIgE >5000 kU/L (Group B) had sIgE measurement for egg, milk, wheat, peanut, and soybean by ImmunoCap from undiluted and 4 serial two-fold dilutions using manufacturer supplied diluent. Myeloma IgE was prepared at an initial dilution of 1:28 and then 7 serial two-fold dilutions were performed. tIgE percenta...
متن کاملPerformance of the PROTIA™ Allergy-Q® System in the Detection of Allergen-specific IgE: A Comparison With the ImmunoCAP® System
PURPOSE The PROTIA™ Allergy-Q® enzyme immunoassay (EIA) is a recently developed screening assay for specific immunoglobulin E (sIgE) for multiple allergens. The ImmunoCAP® fluorescent EIA (FEIA) system is the most widely used method for sIgE detection. In this study, we evaluated the performance of the Allergy-Q® system compared to the ImmunoCAP® system. METHODS We compared the 2 systems usin...
متن کاملInduction and regulation of allergen-specific IgE
The immune response is characterized by an initial rapid activation of the innate defence system, geared at recognizing common structures shared by many microorganisms. This innate immune response is a prerequisite to mount a highly antigenspecific adaptive immune response consisting of T-cell differentiation into effector subsets and B-cell differentiation into antibody-secreting plasma cells....
متن کامل[Detection of allergen specific IgE by AdvanSure Allergy Screen test].
BACKGROUND In vitro serum allergen-specific IgE tests have been routinely used in the clinical diagnosis of allergic diseases. We evaluated the clinical usefulness of a newly introduced multiple antigen screen test, Advansure Allergy Screen (LG Life Science, Korea) (LG-Screen) for the detection of allergen specific IgE. METHODS A total of 180 sera (80 for inhalant and 100 for food panels) wer...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2018
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2017.12.606